Member Name: Ghayoor Abbas Chotana

Title: Visiting Faculty of Chemistry

Qualifications: Ph.D., Michigan State University, USA
PostDoc, Indiana University Bloomington, USA
M.Sc., Quaid-i-Azam University, Islamabad

Phone: + 92 (42) 3572 2670 Ex: 8281

Fax: +92 (42) 3572 2694

Email: ghayoor.abbas@lums.edu.pk

Resaerch Interests: Homogenous Catalysis, Organic Synthetic Methodology, Organometallic & Materials Chemistry

Biography: Dr. Ghayoor received his M.Sc. degree in chemistry from Quaid-i-Azam University Islamabad with distinction. After serving as lecturer in chemistry at GCU Lahore for couple of years, he went to Michigan State University USA for his PhD studies. At MSU he joined Prof. Milton R. Smith III group and studied applications of transition metal catalyzed reactions in organic synthesis. Specifically he studied iridium catalyzed aromatic C–H activation/borylation reactions, and, Palladium catalyzed Suzuki, Sonogashira, and C–S coupling reactions. His Ph.D. research work was the basis for the setting up of a fine chemical company, BoroPharm, by his Ph.D. advisors. He later moved to Indiana University Bloomington and worked as a Postdoctoral associate with Prof. Dan J. Mindiola. His Postdoctoral research work was mainly focused on early transition metal carboamination reactions.

Dr. Ghayoor has a distinguished academic career. He secured first position in all four semesters during his M.Sc. studies at Quaid-i-Azam University Islamabad. He was awarded Ph.D. scholarship/assistantship from Michigan State University for his doctoral work there. He received BruBaker and dissertation completion fellowships while at MSU. He has received US Presidential Green Chemistry Challenge Award 2008 for developing green technology for the preparation of aryl boronic esters.

Dr. Ghayoor has presented his research work in various international conferences including meetings of the American Chemical Society and the US National Organic Symposium. He has also given an invited talk at the Gordon Graduate Organometallic Seminar series. His research results have been published in Journal of the American Chemical Society, Organic Letters, Chemical Communications, and Tetrahedron. He also has five US/European/World Patents to his credit.

Distinctions: US Presidential Green Chemistry Challenge Award 2008
First Position, M.Sc. Chemistry, QAU

Publications and Patents:

7. Ghayoor A. Chotana, Britt A. Vanchura, II, Man-Kin Tse, Richard J. Staples, Robert E. Maleczka, Jr., and Milton R. Smith III. Getting the Sterics Just Right: A Five Coordinate Iridium Trisboryl Complex that Reacts with C–H Bonds at Room Temperature. Chem. Comm. 2009, 38, 5731-5733.

6. Ghayoor A. Chotana, Venkata A. Kallepalli, Robert E. Maleczka, Jr., and Milton R. Smith III. Iridium–catalyzed Borylation of Thiophenes: Versatile, Synthetic Elaboration Founded on Selective C–H Functionalization. Tetrahedron 2008, 64 (26), 6103-6114.

5. Sulagna Paul, Ghayoor A. Chotana, Daniel Holmes, Rebecca C. Reichle, Robert E. Maleczka, Jr., and Milton R. Smith III. Ir-Catalyzed Functionalization of 2-Substituted Indoles at the 7-Position: Nitrogen Directed Aromatic Borylation. J. Am. Chem. Soc. 2006, 128 (49), 15552-15553.

4. Daniel Holmes, Ghayoor A. Chotana, Robert E. Maleczka, Jr., and Milton R. Smith III. One-Pot Borylation/Amination Reactions: Synthesis of Arylamine Boronate Esters from Halogenated Arenes. Org. Lett. 2006, 8 (7), 1407-1410.

3. Ghayoor A. Chotana, Michael A. Rak, and Milton R. Smith III. Sterically Directed Functionalization of Aromatic C–H Bonds: Selective Borylation Ortho to Cyano Groups in Arenes and Heterocycles. J. Am. Chem. Soc. 2005, 127 (30), 10539-10544.

2. M. Ikram, M. A. Rauf, Ghayoor A. Chotana, and N. Bukhari. Levels of Lead in Solvent and Water Based Paints Manufactured in Pakistan. Sci. Intl. (Lahore) 2000, 12 (3), 255-256.

1. M. Ikram, M. A. Rauf, S. S. Tahir, and Ghayoor A. Chotana. Levels of Selected Toxic Metals in Solvent Based Paints Manufactured in Pakistan. Int. J. Environ. Studies, 1999, 56 (3), 234-235.

Patents

3. Milton R. Smith III., Robert E. Maleczka, Jr., Ghayoor A. Chotana, Venkata A. Kallepalli, and Sulagna Paul. Process for the Preparation of Borylated Thiophenes. U.S. Pat. Appl. Publ. 20080091035.

2. Milton R. Smith III., Robert E. Maleczka, Jr., Ghayoor A. Chotana, and Sulagna Paul. Process for the Preparation of 2-Substituted-7-Boryl Indoles and Compounds. U.S. Pat. Appl. Publ. 20080167476.

1. Milton R. Smith III., Robert E. Maleczka, Jr., and Ghayoor A. Chotana. Catalytic Ortho Borylation of Substituted Benzonitriles and Cyano Substituted Heteroaromatics. U.S. Pat. Appl. Publ. 20060281939, WO/2006/135705, and EP/2008/1904441.